JPS6242905B2 - - Google Patents

Info

Publication number
JPS6242905B2
JPS6242905B2 JP52005446A JP544677A JPS6242905B2 JP S6242905 B2 JPS6242905 B2 JP S6242905B2 JP 52005446 A JP52005446 A JP 52005446A JP 544677 A JP544677 A JP 544677A JP S6242905 B2 JPS6242905 B2 JP S6242905B2
Authority
JP
Japan
Prior art keywords
formula
piperazine
hydrogen atom
cyclohexylamine
methyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52005446A
Other languages
English (en)
Japanese (ja)
Other versions
JPS52111583A (en
Inventor
Korubiimora Kamiro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAMITSURO KORUBI SpA
Original Assignee
KAMITSURO KORUBI SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KAMITSURO KORUBI SpA filed Critical KAMITSURO KORUBI SpA
Publication of JPS52111583A publication Critical patent/JPS52111583A/ja
Publication of JPS6242905B2 publication Critical patent/JPS6242905B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP544677A 1976-01-23 1977-01-22 Piperazine derivative and its homologues and method for their preparation and antiitumor and antiiconvulsant agent containing same Granted JPS52111583A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19517/76A IT1054961B (it) 1976-01-23 1976-01-23 Derivati della piperazina adatti come agenti anti ulcera

Publications (2)

Publication Number Publication Date
JPS52111583A JPS52111583A (en) 1977-09-19
JPS6242905B2 true JPS6242905B2 (en]) 1987-09-10

Family

ID=11158695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP544677A Granted JPS52111583A (en) 1976-01-23 1977-01-22 Piperazine derivative and its homologues and method for their preparation and antiitumor and antiiconvulsant agent containing same

Country Status (9)

Country Link
US (2) US4123530A (en])
JP (1) JPS52111583A (en])
BE (1) BE850628A (en])
CH (1) CH624944A5 (en])
DE (1) DE2702537C2 (en])
FR (1) FR2338938A1 (en])
GB (1) GB1567958A (en])
IT (1) IT1054961B (en])
NL (1) NL7700425A (en])

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1054961B (it) * 1976-01-23 1981-11-30 Corvi Camillo Spa Derivati della piperazina adatti come agenti anti ulcera
US4666911A (en) * 1981-07-14 1987-05-19 Taiho Pharmaceutical Company Limited Allophanoylpiperazine compound and analgesic composition containing same as active ingredient
IT1150759B (it) * 1982-04-05 1986-12-17 Corvi Camillo Spa Complessi organometallici di n-cicloesil-piperazino-acetammidi o propionammidi, loro preparazione e impiego come farmaci antiulcera-antisecretivi-tamponanti
US4477646A (en) * 1983-08-24 1984-10-16 The Dow Chemical Company Piperazinoethyl ureas
JPS6147466A (ja) * 1984-08-10 1986-03-07 Dainippon Pharmaceut Co Ltd アミン誘導体
US5182284A (en) * 1990-01-26 1993-01-26 Taiho Pharmaceutical Co., Ltd. Piperazine compounds, processes for preparation thereof and medical uses thereof
US6048900A (en) * 1998-02-13 2000-04-11 Bayer Corporation Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
US6245817B1 (en) 1997-02-14 2001-06-12 Bayer Corporation NPY5 receptor antagonists and methods for using same
CA2251368A1 (en) * 1997-02-14 1998-08-20 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
ES2326800T3 (es) * 2002-06-24 2009-10-20 Janssen Pharmaceutica Nv Proceso para la produccion de n-(2,6-dimetil-fenil)-2-piperazin-1-il-acetamida.
WO2011000945A2 (en) 2009-07-03 2011-01-06 Nensius Research A/S Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the cns
JP5838628B2 (ja) * 2011-07-25 2016-01-06 東ソー株式会社 Ｎ−アルキルピペラジン類の製造方法
WO2019079243A1 (en) * 2017-10-17 2019-04-25 Albert Einstein College Of Medicine, Inc. MITOFUSIN ACTIVATORS AND USES THEREOF

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1186495A (en) * 1968-02-20 1970-04-02 Delalande Sa 0-[3-(4-Fluorobenzoyl) Proplyl]-4-Substituted Piperazines, their Acid Addition Salts and their method of preparation
DE1795375A1 (de) * 1968-09-21 1972-01-05 Boehringer Mannheim Gmbh Basische AEther und Verfahren zur Herstellung derselben
DE2034625A1 (en]) * 1969-08-14 1971-02-25
IT1054961B (it) * 1976-01-23 1981-11-30 Corvi Camillo Spa Derivati della piperazina adatti come agenti anti ulcera

Also Published As

Publication number Publication date
GB1567958A (en) 1980-05-21
NL7700425A (nl) 1977-07-26
DE2702537C2 (de) 1987-03-12
US4123530A (en) 1978-10-31
JPS52111583A (en) 1977-09-19
FR2338938A1 (fr) 1977-08-19
BE850628A (fr) 1977-05-16
US4278796A (en) 1981-07-14
FR2338938B1 (en]) 1979-10-05
DE2702537A1 (de) 1977-07-28
IT1054961B (it) 1981-11-30
CH624944A5 (en]) 1981-08-31

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